Oliver Distler Selected Research

Fibrosis (Cirrhosis)

1/2022	Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis.
2/2021	The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis.
1/2021	Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs).
12/2020	cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis.
11/2020	Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis.
11/2020	Association of Anti-Topoisomerase I Antibodies of the IgM Isotype With Disease Progression in Anti-Topoisomerase I-Positive Systemic Sclerosis.
10/2020	Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial.
5/2020	Intravenous versus oral cyclophosphamide for lung and/or skin fibrosis in systemic sclerosis: an indirect comparison from EUSTAR and randomised controlled trials.
1/2020	Validation of the suction device Nimble for the assessment of skin fibrosis in systemic sclerosis.
1/2020	Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse.

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Oliver Distler Research Topics

Disease

115	Systemic Scleroderma (Systemic Sclerosis) 12/2022 - 01/2002
107	Fibrosis (Cirrhosis) 01/2022 - 10/2005
23	Inflammation (Inflammations) 01/2022 - 10/2002
21	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2022 - 11/2013
18	Pulmonary Arterial Hypertension 10/2022 - 07/2011
14	Pulmonary Hypertension 10/2022 - 05/2008
10	Hypoxia (Hypoxemia) 01/2022 - 03/2002
10	Rheumatoid Arthritis 01/2022 - 10/2002
10	Diffuse Scleroderma (Progressive Systemic Sclerosis) 07/2021 - 01/2017
9	Idiopathic Pulmonary Fibrosis 01/2022 - 05/2016
9	Arthritis (Polyarthritis) 01/2022 - 04/2006
9	Disease Progression 12/2021 - 05/2016
9	Neoplasms (Cancer) 11/2021 - 05/2006
8	digital ulcers 05/2020 - 10/2009
7	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 02/2007
7	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2020 - 08/2008
6	Lung Diseases (Lung Disease) 10/2022 - 06/2003
6	Rheumatic Diseases (Rheumatism) 01/2021 - 05/2006
6	Bronchiolitis Obliterans Syndrome 01/2020 - 01/2010
6	Vascular Diseases (Vascular Disease) 05/2011 - 10/2002
5	Pain (Aches) 02/2022 - 01/2010
5	Connective Tissue Diseases (Connective Tissue Disease) 01/2019 - 08/2008
4	Mixed Connective Tissue Disease (MCTD) 09/2016 - 08/2008
4	Ulcer 01/2016 - 01/2002
3	Familial Primary Pulmonary Hypertension 10/2022 - 01/2015
3	Necrosis 01/2022 - 01/2007
3	COVID-19 01/2022 - 01/2020
3	Muscular Diseases (Myopathy) 07/2021 - 07/2013
3	Heart Failure 01/2020 - 01/2014
3	Telangiectasis (Telangiectasia) 06/2014 - 11/2013
3	Osteoarthritis 04/2007 - 05/2004
2	Vasculitis (Vasculitides) 02/2022 - 01/2016
2	Diarrhea 01/2022 - 01/2019
2	Raynaud Disease (Raynaud's Disease) 01/2021 - 06/2014

Drug/Important Bio-Agent (IBA)

47	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022 - 01/2007
25	CollagenIBA 01/2021 - 10/2005
15	indium-bleomycinIBA 01/2018 - 08/2007
14	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021 - 05/2012
12	nintedanibIBA 12/2022 - 05/2016
11	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2009
11	CytokinesIBA 01/2021 - 10/2002
11	Hydroxyproline (4 Hydroxyproline)IBA 01/2019 - 11/2010
10	Carbon MonoxideIBA 10/2022 - 01/2014
10	AntibodiesIBA 01/2022 - 01/2012
10	AutoantibodiesIBA 01/2022 - 04/2009
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 01/2002
8	Tyrosine Kinase InhibitorsIBA 01/2021 - 02/2008
8	Imatinib Mesylate (Gleevec)FDA Link 11/2012 - 01/2007
7	Pharmaceutical PreparationsIBA 02/2021 - 01/2007
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2007
7	EnzymesIBA 05/2020 - 12/2005
6	riociguatIBA 01/2022 - 08/2015
6	Soluble Guanylyl CyclaseIBA 01/2020 - 06/2012
6	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 11/2017 - 04/2007
6	Phosphotransferases (Kinase)IBA 11/2017 - 07/2008
5	Abatacept (Orencia)FDA Link 12/2020 - 07/2013
5	tocilizumab (atlizumab)FDA Link 10/2020 - 07/2013
5	Transcription Factors (Transcription Factor)IBA 01/2020 - 12/2009
5	Fos-Related Antigen-2IBA 01/2018 - 12/2009
5	CateninsIBA 05/2017 - 05/2012
4	anti-scl-70 autoantibodiesIBA 11/2022 - 12/2015
4	C-Reactive ProteinIBA 01/2022 - 01/2017
4	RNA (Ribonucleic Acid)IBA 01/2022 - 04/2007
4	MicroRNAs (MicroRNA)IBA 06/2021 - 06/2010
4	beta-cyclodextrin tetradecasulfate (CTDS)IBA 01/2021 - 12/2013
4	DNA (Deoxyribonucleic Acid)IBA 11/2020 - 04/2007
4	Oxygen (Dioxygen)IBA 05/2020 - 07/2004
4	Rituximab (Mabthera)FDA Link 01/2019 - 06/2015
4	Small Interfering RNA (siRNA)IBA 03/2016 - 05/2012
4	nilotinib FDA Link 12/2013 - 07/2008
4	Extracellular Matrix ProteinsIBA 06/2013 - 12/2007
3	SteroidsIBA 01/2022 - 01/2019
3	Biological ProductsIBA 01/2022 - 02/2011
3	Creatine Kinase (Creatine Phosphokinase)IBA 07/2021 - 06/2015
3	Messenger RNA (mRNA)IBA 06/2021 - 04/2007
3	Fibronectins (Fibronectin)IBA 01/2021 - 12/2007
3	Histones (Histone)IBA 01/2021 - 04/2007
3	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 12/2006
3	ametantrone (HAQ)IBA 10/2020 - 11/2011
3	Interleukin-6 (Interleukin 6)IBA 10/2020 - 04/2006
3	Endothelin Receptor AntagonistsIBA 01/2020 - 05/2008
3	LigandsIBA 01/2020 - 03/2014
3	AdiponectinIBA 01/2019 - 04/2006
3	Transforming Growth Factor beta (TGF-beta)IBA 01/2018 - 01/2009
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 11/2017 - 04/2007
3	trichostatin A (A 300)IBA 09/2014 - 08/2007
3	LipoxinsIBA 06/2012 - 12/2005
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 05/2012 - 12/2009
2	Brain Natriuretic Peptide (Natrecor)FDA Link 10/2022 - 01/2022
2	InterleukinsIBA 01/2022 - 08/2017
2	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 05/2008
2	VaccinesIBA 01/2022 - 01/2022
2	anticentromere antibodyIBA 12/2021 - 02/2020
2	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 07/2021 - 01/2021
2	RNA Polymerase IIIIBA 07/2021 - 01/2017

Therapy/Procedure

33	Therapeutics 10/2022 - 01/2007
4	Stem Cell Transplantation 01/2019 - 02/2008
3	Injections 02/2022 - 01/2019
3	Precision Medicine 02/2021 - 06/2014
2	Transplantation 01/2021 - 04/2009